Ezetimibe
Chemical name:
1-(4-Fluorophenyl)-(3R)-[3-(4-fluorophenyl)-3S-hydroxy
Molecular Formula C24H21F2NO3
Molecular Weight 409.43
CAS Registry Number 163222-33-1
Intermediate:
4-fluoro-N-(hydroxyphenyl)methylene-benzenamine
CAS Registry Number 3 3 8 2-63-6
5-(4-fluorophenyl)-5-ketopentanoic acid
CAS Registry Number 149437-76-3
3-[5-(4-fluorophenyl)-1, 5-dioxopentyl]-4-phenyl-(4S)-2-oxazolidinone
CAS Registry Number 189028-93-1
Pregabalin
[Chemical Name]:
(3S)-3-(aminomethyl)-5-methylhexanoic acid
[Structure]:
[Molecule]:C8H17NO2
[Molecular weight]:159.23
[CAS]:148553-50-8
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items
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specification
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results
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description
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yellow to light tan powder, having an odor
suggestive of cereals, is hygroscopic, and is affected by long exposure to light, heat and air.
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conforms
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solubility
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freely soluble in dimethylformamide and in dimethyl sulfoxide; slightly to sparingly soluble in methanol, in n-propyl alcohol, and in n-butyl alcohol; practically insoluble in water and in alcohol; insoluble in chloroform and in ether
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conforms
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identification
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ratio of its absorbance at 230nm to this at 279nm is between 0.90 and 1.25
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conforms
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ph
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6.0 ~ 8.0
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7.2
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loss on drying
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not more than 5.0%
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3.2%
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assay
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not less than 4400μ/mg
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6260μ/mg
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conclusion:
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the results conform to the standard of usp28.
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